Dermatologist-designed
The Calming Cream was formulated by Dr. Brandon Kirsch from years of treating inflammatory skin disease in clinical practice. Not a generic OTC product.


Roflumilast 0.2% with calamine 5%, designed by a board-certified dermatologist and prescribed online. Steroid-free relief for mild-to-moderate eczema or psoriasis, gentle enough for the face. One flat $70 for a 90-day supply, with clinician review and free shipping included.
Boutique care, not a chatbot. Text a real clinician 24/7.
Prescription required. If you are not eligible, you receive a full refund.
| KindleeRxThe Calming Cream | Brand nameZoryve | |
|---|---|---|
| What it is | Roflumilast 0.2% + calamine 5% | Brand-name roflumilast |
| Typical cash price | $70 for 90 days | About $900+ cash |
| Doctor visit | Included | Separate, billed to you |
| Size | 80 grams, 90 days | 60 grams |
Same PDE4 inhibitor class. The Calming Cream is a compounded prescription option, not Zoryve, and not affiliated with Zoryve or Arcutis.
KindleeRx is built for patients who want a transparent, cash-pay, roflumilast-based option.
Prescription required. If you are not eligible, you receive a full refund.
KindleeRx is not a drugstore for medication. We are a company created and majority owned by medical professionals, and Dr. Brandon Kirsch designed The Calming Cream: a compounded, roflumilast-based prescription cream built from years of treating inflammatory skin conditions in clinical practice.

Founder and Chief Medical Officer
“Roflumilast delivers excellent results with a strong safety profile, steroid-free and gentle enough for daily use. The Calming Cream makes that care accessible at a fair, transparent price, with a clinician you can message 24/7.”
Board-certified dermatologist. Pharmaceutical drug development background. 15+ years in clinical medicine.
The Calming Cream was formulated by Dr. Brandon Kirsch from years of treating inflammatory skin disease in clinical practice. Not a generic OTC product.
90 days of unlimited messaging with your clinician, 24/7. Real replies seven days a week. No appointment, no waiting room.
Your prescription is compounded by LegitScript-certified U.S. pharmacies that meet strict USP compounding standards. Every order is reviewed by a licensed pharmacist before it ships.










Roflumilast is a steroid-free PDE4 inhibitor used in modern eczema and psoriasis care. The Calming Cream pairs it with calamine 5% for added itch and redness relief, so you get an anti-inflammatory pathway and everyday comfort in one compounded prescription cream.
A steroid-free PDE4 inhibitor that targets the inflammatory pathway behind eczema and psoriasis, without the skin thinning associated with long-term steroid use.
A long-trusted skin soother that calms itch and redness, supporting day-to-day comfort while your skin settles.
One simple once-daily cream: an anti-inflammatory pathway plus comfort and barrier support, gentle enough for sensitive areas including the face and skin folds.




Real patient · Unretouched. No touch-ups.
“Kindlee eczema cream has worked wonders on my hands! I have dealt with eczema that has been difficult to treat for years, and this cream has cleared things up significantly. Best of all, no harsh steroids. So grateful to have found the providers at kindlee!”
Prescription roflumilast, without the brand-name price.
A compounded roflumilast 0.2% and calamine 5% cream for eligible patients with mild to moderate eczema or psoriasis, on a simple once-daily routine.
$70 for a 90-day supply. $0.78 a day. Consult and free shipping included.
Real KindleeRx patients. Unretouched. Individual results may vary.

Share your relevant medical history and current medications in a short online questionnaire, plus a few photos of your skin so your clinician can evaluate severity.
≈ 5 minutesA licensed clinician reviews your photos, health, and medications, confirms mild to moderate eczema or psoriasis, and prescribes The Calming Cream if it is right for you.
Within 24 hoursIf approved, your Calming Cream is compounded by an accredited U.S. pharmacy and shipped free to your door.
Ships in 5 to 7 daysMessage your clinician 24/7 for refills or questions as your skin responds. No appointment, no waiting room.
90 days includedMedical consult required. Not all patients qualify.
Your roflumilast-based prescription cream, sized for a full 90 days.
Licensed clinician review against dermatologist standards before prescribing.
90 days of unlimited messaging with your clinician.
Letter of medical necessity for pre-tax reimbursement.
Your prescription ships free to your door.
90-day satisfaction guarantee or full refund.
Most patients see meaningful improvement within 2 to 6 weeks. Long-term control comes from staying on the once-daily routine.
$70 for a 90-day supply. Prescription cream, medical consult, and free shipping all included.
Just $0.78 a day
Renews every 90 days. Cancel anytime.
Medical consult required. Not all patients qualify.
You are charged when you start. Your clinician determines whether prescribing is medically appropriate. Compounded medications are not FDA approved and are not evaluated by the FDA for safety, effectiveness, or quality.
Not eligible, or not satisfied? Full refund.
Zoryve, roflumilast, pricing, and how prescribing works.
No. The Calming Cream is not Zoryve and is not affiliated with Zoryve or its maker, Arcutis. It is a compounded prescription cream that contains roflumilast (the same PDE4 inhibitor class as Zoryve) combined with calamine 5%. It is not FDA-approved.
No. There is no FDA-approved generic of Zoryve, and The Calming Cream is not one. It is a compounded prescription medication, prepared by a licensed pharmacy using roflumilast 0.2% and calamine 5%. Compounded medications are not reviewed by the FDA for safety, effectiveness, or quality.
The Calming Cream is a cash-pay, compounded prescription, so there is no brand-name pricing and no insurance billing. You pay one flat price of $70 for a 90-day supply, about $0.78 a day, with the consult and free shipping included. Brand-name Zoryve is priced and distributed differently, and what you pay can depend heavily on insurance or a manufacturer savings card.
No. You do not need an existing prescription. You complete a short online visit, and a licensed clinician reviews your history and photos to decide whether The Calming Cream is appropriate for you. If it is, they write the prescription. Not all patients qualify.
Roflumilast is often used on sensitive areas, and many patients apply The Calming Cream to the face and skin folds. Your clinician will give you personalized direction on where and how to use it based on your skin and history. Always follow your clinician's instructions.
If a clinician determines that treatment is not appropriate for you, you receive a full refund, including the $20 consult fee. There is no risk in completing the online visit to find out whether you qualify.
The most commonly reported effects with topical roflumilast are application-site reactions such as mild stinging, burning, or irritation, along with headache and, less often, nausea or diarrhea. Calamine is generally well tolerated. This is not a complete list. Your clinician will review the risks with you, and you should report any reaction that concerns you.
No. The Calming Cream is a compounded prescription medication and is not FDA-approved. Compounded medications are prepared by a licensed pharmacy for an individual patient and are not reviewed by the FDA for safety, effectiveness, or quality. Brand-name Zoryve is FDA-approved; The Calming Cream is a different, compounded option and is not affiliated with Zoryve or Arcutis.
KindleeRx is a physician-led telehealth practice for prescription-strength dermatology and wellness care. No chatbots. No insurance required. The name Kindlee comes from the word kind. It shows up as a fair, transparent price and a clinician who actually answers. We built it to care for people the way we would want our own families cared for.
Real clinicians who genuinely love their work, led by a board-certified dermatologist. You talk to a person, never a chatbot.
One flat price, kept as low as we can, with no surprises and no insurance required.
Personalized plans and real answers from your clinician, seven days a week. Nobody should have to wait on their care.
Start with a short online visit. A personalized plan follows, and a clinician is here seven days a week.
For eligible patients with mild to moderate eczema or psoriasis. Clinician review, prescription if approved, 90 days of support, and free shipping, with a full refund if you are not eligible.
$70 for a 90-day supply. $0.78 a day.
Not Zoryve, not a generic version of Zoryve, and not affiliated with Arcutis. Compounded prescription medication; not FDA-approved.