Melasma

Personalized Dark Spot Treatment

Medical Consultation
Answer a few quick questions and upload pictures of your melasma for your consultation with a board-certified dermatologist.
Diagnosis
Your dedicated physician will review your information and formulate your personalized prescription.
Delivered
Your one-of-a-kind prescription will arrive at your front door, with free shipping.
Evolution of Care
When it’s time for a refill, we adjust your treatment plan based on your progress for optimal long-term results.

Available in 4 Formulations

100% custom-formulated for your unique skin needs

Gentle Treatment

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Gentle Treatment:

An effective option for those who want something stronger than over-the-counter products, but who also want to minimize the potential for skin irritation. Your dermatologist will personalize the final prescription to your skin.
Hydroquinone: 6%
Adapelene: 0.1%
Desonide: 0.05%
Two-Month Supply (30 grams)

Intensive Treatment

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HQ Free

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Oral Tranexamic Acid

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Available in 4 Formulations

100% custom-formulated for your unique skin needs

Gentle Treatment

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Gentle Treatment:

An effective option for those who want something stronger than over-the-counter products, but who also want to minimize the potential for skin irritation. Your dermatologist will personalize the final prescription to your skin.
Hydroquinone: 6%
Adapalene: 0.1%
Desonide: 0.05%
Two-Month Supply (30 grams)

Intensive Treatment

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Intensive Treatment:

Up to 6x stronger than over-the-counter hydroquinone creams, this is our strongest formulation. It is effective at clearing up larger areas and stubborn spots. Your dermatologist will personalize the final prescription to your skin.
Hydroquinone: 12%
Adapalene: 0.1%
Desonide: 0.05%
Two-Month Supply (30 grams)

Oral Tranexamic Acid

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Oral Tranexamic Acid:

Oral tranexamic acid is reserved for those who have tried and failed other treatments for their skin hyperpigmentation. Recent studies have demonstrated up to a 89.7% improvement in melasma with oral tranexamic acid, which is very high, considering the condition is often highly resistant to therapy. This medicine should not be taken by individuals with a personal or family history of blood clots, heart disease and stroke. Your dermatologist will require you to complete a thorough medical history before approving this treatment.
Tranexamic Acid 250mg (Two-Month Supply, 120 Tablets)

HQ Free

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Hydroquinone Free/Maintenance Treatment:

A proven option for those who want their prescription without hydroquinone. Works best for mild hyperpigmentation or to maintain clearance achieved with hydroquinone. Your dermatologist will tailor the final product prescription to your skin.
Adapalene: 0.1%
Azelaic Acid: 12%
Kojic Acid 2%
Arbutin 2%
Two-Month Supply (30 grams)

Melasma Treatment Results

Personalized Prescription Dark Spot Corrector Formulation

$70

→ One custom-formulated bottle of topical cream

→ An approximately 2-month supply

→ Medical consultation included

Beyond receiving fantastic medical care without ever leaving your home, ClearifiRx is designed to be able to be used continuously… so your melasma keeps getting better and better, no breaks needed.

Brandon Kirsch, MD, FAAD | CHIEF EXECUTIVE OFFICER, FOUNDER

Beyond receiving fantastic medical care without ever leaving your home, ClearifiRx is designed to be able to be used continuously… so your melasma keeps getting better and better, no breaks needed.

Brandon Kirsch, MD, FAAD | CHIEF EXECUTIVE OFFICER, FOUNDER

See real results with proven pharmaceutical ingredients.

We use only medical-grade active ingredients in ClearifiRx formulations.

Adapalene

Adapalene disrupts the transfer of melanosomes and speeds up your body’s removal of pigmented skin cells.

Azelaic Acid

Azelaic acid is an anti-inflammatory and a tyrosinase inhibitor that reduces the synthesis of melanin.

Arbutin

Arbutin works by inhibiting the cellular enzymes in skin cells that create pigment.

Desonide

Desonide prevents the release of substances in the skin that cause inflammation and leads to skin darkening.

Ferulic Acid

Ferulic acid protects your skin against free radicals when used in combination with other antioxidants like vitamins C and E.

Hydroquinone

Hydroquinone interrupts the formation and synthesis of melanin to help lighten dark patches of skin.

Kojic Acid

Kojic acid traps free radicals and acts as a tyrosinase inhibitor to stop the production of melanin.

Lipoic Acid

Lipoic Acid is an antioxidant that is 400 times stronger than vitamin C E. It decreases swelling, inflammation, and puffiness.

Tretinoin

Tretinoin is a form of vitamin A that reduces the appearance of skin discoloration.

Ascorbic Acid (Vitamin C)

Ascorbic acid acts as a reducing agent at various oxidative steps of pigment formation inhibiting the process (it can also keep your cut apples from turning brown!).

All our providers are board-certified physicians.

No PAs. No Nurse Practitioners.

You deserve
exceptional care.

No waiting for appointments

No costly pharmacy trips

All providers are board-certified physicians

I personally recommend my patients use ClearifiRx. As a doctor, I have a responsibility to steer my patients towards a treatment option that works… and ClearifiRx not only works, it changes my patients’ lives.

Patricia Walker, MD, PhD, FAAD | EXECUTIVE CHAIRMAN